The PopMedNet™ network Portal is a dedicated secure website which manages all network interactions. Functions of the Portal include managing user settings, composing and routing requests, managing results, creating and enforcing permission settings, and audit reporting.

The Portal is based on a Microsoft .Net technology stack using ASP.NET MVC for the web site framework, C# as the programming language, and Managed Extension Framework (MEF) to implement request model plug-ins, Entity Framework (EF 6) to support the data model and SQL Server (2016) for persistence.